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Several more treatment arms are expected to open later this year.The drugs included in the trial have either been approved by the U. Food and Drug Administration (FDA) for another cancer or are still being tested in other clinical trials but have shown some effectiveness against tumors with a particular genetic change.
Patients, families, and clinicians can also contact NCI’s Cancer Information Service to learn more about the COMET study.
A secondary goal for the trial is to determine the percentage of patients whose disease does not worsen for at least six months. In addition to assessing the objective response rate and progression-free survival, researchers will also determine time to progression of the cancer and evaluate the side effects of the treatments.